After years of a tumultuous relationship with her husband, Tamy's eating addiction has caused her weight to balloon over 500-lbs. She has become a hermit after years of s ...

Lisa's struggle with her weight began as a child and significantly worsened after witnessing her brother's murder. Now bedridden and unable to care for herself, Lisa must ...

James LB Bonner spent his early life trying to prove himself to his adoptive family, but after losing a leg and battling obesity, LB must take a new path to save his heal ...

Unable to stand for more than a short period of time, Karina's weight has placed a burden on her parents and driven a wedge between she and her sister. Can Karina lose we ...

A woman whose extreme obesity has left her nearly immobile must overcome both her physical and emotional pain if she is ever to live a normal life again. ...

After meeting and falling in love at a barriatric rehab center, Lee and Rena are battling health and anger issues while taking a desperate, second attempt to save their r ...

After meeting and falling in love at a barriatric rehab center, Lee and Rena are battling health and anger issues while taking a desperate, second attempt to save their r ...

Fearing he'll suffer the same fate as 700-pound brother David, Benji hopes to be able to support both himself and his brother on their life-or-death weight loss journey. ...

A woman whose extreme obesity has left her nearly immobile must overcome both her physical and emotional pain if she is ever to live a normal life again. ...

After meeting and falling in love at a barriatric rehab center, Lee and Rena are battling health and anger issues while taking a desperate, second attempt to save their r ...

After meeting and falling in love at a barriatric rehab center, Lee and Rena are battling health and anger issues while taking a desperate, second attempt to save their r ...

Gastric surgery freed Brittani from her housebound life, but to achieve her ideal body she'll have to endure two more painful surgeries. Sean's super-obesity nearly kille ...

Twins Kandi and Brandi have a combined weight totaling over 1100lbs. These inseparable twins fear losing each other to obesity, so they make a change together. But a life ...

Christina's weight loss has gone too far, too fast, and now threatens her life. After losing 300lbs, Paula must endure more surgery to deal with a body entirely covered i ...

Melissa finds herself overwhelmed with four children, a marriage on the rocks, and an unexpected pregnancy. When Ashley's weight loss journey hits a wall, she sets out to ...

At 600 pounds, Lupe spent the last 10 years in bed and totally dependent on her husband. A doctor in Texas is her only hope for change. A cross-country move to save her l ...

At 650lbs, Randy's food addiction led to the loss of his marriage and visits with his daughter. To regain control of his life, he endures a rigorous pre-surgery diet, sur ...

At over 700lbs, Teretha's life is confined to a bed which is a far cry from her former job representing Detroit's healthy eating program. Her adoring family fears losing ...

Dottie loves being a mom but, at over 600lbs, she's on the verge of leaving her 2 young children motherless. She agrees to a drastic new diet, but her child's life-threat ...

600-pound June copes with the tragic death of her son by eating. After gastric bypass surgery, she must confront the emotional issues driving her food compulsion. If she ...

At over 600 pounds, Brittani's eating has enslaved her and left her marriage without intimacy. She must seek help before her body gives out. ...

Pivotal moments, whether tragic breaking points or ultimate triumphs, decide the success or failure of individuals struggling with extreme obesity. They must face the rea ...

Olivia strives to weigh-in under 200-lbs as she lives by herself for the first time and suffers an unexpected loss. Battling a series of let downs, James fights to reach ...

Ashley's career was derailed after she was let go due to her excessive weight. Will she be able to turn her life around and achieve her goal of owning a childcare facilit ...

750-lb Henry begins his weight loss journey in the hopes of transforming himself in time to attend his high school reunion. ...

Love motivates 660-lb Donald to begin his weight loss journey. ...

650-lb Melissa begins her seven-year weight loss journey. ...