When multiple children get sick from lead poisoning, Morgan Edge points the finger at Lena and blames her creation of the lead bomb she made to save National City from th ...

Kara investigates a secretive new group whose leader, Thomas Coville, has a mysterious connection to Supergirl. Meanwhile, Samantha feels like she's letting Ruby down. ...

Maggie reaches out to her estranged father when Eliza throws her and Alex a wedding shower, while Supergirl joins J'onn on a personal mission. ...

Psi, a thief with psychic powers, attacks National City. Able to immobilize people by tapping into their worst fears, Psi proves a formidable opponent for Supergirl. Mean ...

Kara deals with the loss of Mon-El by focusing all her energy on being Supergirl and the mysterious new threat against National City. Alex confesses a secret to Maggie ab ...

Supergirl challenges Rhea to battle to save National City. Meanwhile, Superman returns and Cat Grant offers Supergirl some sage advice. ...

Supergirl struggles to decide whether or not to obey the President's orders regarding Rhea's latest actions. Meanwhile, Cat Grant returns to National City. ...

When an alien attacks National City, Supergirl and the DEO learn the alien is a Phorian, an otherwise peaceful race with telekinetic powers. Guardian gets a lead on the P ...

Alex is kidnapped and the kidnapper threatens to kill her unless Supergirl releases a notorious criminal from prison. Supergirl and Maggie have always had different appro ...

Lena's ex-boyfriend, Jack Spheer, comes to National City to unveil his big breakthrough in nano-technology, which has the potential to eradicate all diseases. Lena asks K ...

A large bounty is put out on Supergirl and aliens from far and near attack National City intent on taking out the woman of steel. Alex and Maggie run into Maggie's ex-gir ...

A new villain (guest star Teri Hatcher) comes to National City, putting Supergirl on high alert. Meanwhile, Winn's girlfriend, Lyra, gets Winn in trouble with the law. Ma ...

As Alex searches for Jeremiah and Kara investigates a series of alien kidnappings, the sisters realize they must break the rules to foil a new Cadmus plot. In an effort t ...

When Jeremiah Danvers is rescued from Cadmus, Alex and Kara are thrilled to have their father back. The Danvers arrange a family dinner to celebrate but things go awry wh ...

Valentine's day special episode. Alex is super excited for her first Valentine's Day with a girlfriend, but Maggie is not keen on the Hallmark holiday, which leads to the ...

After Metallo breaks out of prison and frees Lillian Luthor, the police blame Lena for his escape and arrest her. Despite overwhelming evidence, Kara refuses to believe h ...

Armek, a White Martian, descends on National City intent on taking M'gann back to Mars to face her punishment as a traitor. Hank and Supergirl determine the best way to k ...

After Livewire seemingly breaks out of prison, Supergirl is intent on recapturing her. After training Mon-El, Supergirl takes him with her when she sees Livewire attack t ...

Kara is moved by the story of a missing woman named Izzy and decides to investigate despite Snapper Carr's order to leave it alone. Kara takes Mon-El with her to the last ...

Eliza comes to town to celebrate Thanksgiving with her daughters. Alex decides it's time to come out to her mother; Kara is shocked when Eliza suggests Mon-El has feeling ...

While Guardian tries to clear his name after being accused of a murder committed by another vigilante, Supergirl heads out on a solo mission to rescue Mon-El who has been ...

The Guardian arrives to lend a hand when an alien parasite drains Supergirl of her power. Mon-El contemplates his motives when he considers a new career. Alex faces a new ...

Supergirl must beat a ruthless new gang who has been armed with dangerous new alien technology. When Cadmus sends a video to the DEO, the team realizes Cadmus is the one ...

When Kara and Alex investigate the murder of an unregistered alien, the trail leads to an alien fight club run by Roulette, the ringmaster who commands aliens to fight in ...

When the President arrives to sign an order giving amnesty to aliens. At the DEO, the man who arrived in the craft, awakens and has powers like Supergirl and leaves. Kara ...

Supergirl is hurt by a kryptonite-powered villain sent by Cadmus to attack National City. Superman blames Hank since the kryptonite was stolen from the DEO. In the meanti ...

When a new threat emerges in National City, Kara/Supergirl teams up with her cousin, Clark Kent/Superman, to stop it. Kara is thrilled to have family in town but it leave ...

Supergirl is forced to do battle with an unexpected enemy as she risks everything - including her life - to stop Non and Indigo from destroying everyone on Earth. ...

Non activates Myriad which turns all humans in National City to mindless zombies under his control. Supergirl is all alone and discover two people who are not affected. S ...

When former CatCo employee, Siobahn Smythe upset at how her life is going discovers something odd about herself. She then goes to a relative who tells her of their family ...

J'onn J'onzz reveals how he met Jeremiah Danvers and assumed the identity of Hank Henshaw. ...

Red Kryptonite makes Kara malicious and dangerous while Cat appears on The Talk (2010) to discuss Supergirl. ...